Pentobarbital will decrease the level or effect of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of levoketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Acting as both a sedative and a hypnotic, pentobarbital can be prescribed for the short-term... https://pageoftoday.com/story5761041/pentobarbital-uses-pu%C3%B2-essere-divertente-per-chiunque