Selective degradation of dopaminergic neurons within the substantia nigra, along with the existence of intraneuronal aggregates termed Lewy bodies, are the principle pathological hallmarks of Parkinson's disease (PD). The commonest indicators of PD are bradykinesia, rigidity and tremor. Dopaminergic neurons consume a great deal of ATP to reverse Ca2+ inflow https://simonzeinp.verybigblog.com/23287613/ap-iii-a4-no-further-a-mystery